Saturday, September 21, 2019

American And Korean Student Culture

American And Korean Student Culture In the current essay we will review the Cultural differences between American students and Korean students. In the modern world cultural relations are very important. Due to the globalization countries cooperate more closely and build new relationships built on the current trends. Although the cultural differences are considerable, there are many common things that can be found in different cultures. Modern people have almost unique goals in several areas, as the majority of the population wants to study and then to find a job that will suit a person. There are certain differences between American and Korean student in culture and other aspects. For example, according to Kara Miller (2009), among American students very often there is no change in effort and no improvement in time management. Cultural differences between American students and Korean students Often, it is difficult to balance studying and playing games and staying online. By the time students are in college, habits can be tough to change. If youre used to playing video games like Modern Warfare or Halo all night, how do you fit in four hours of homework? Or rest up for class? Sometimes, even foreign students do better in studies and have more intentions to study and to learn the foreign language. According to Kara Miller (2009), Too many 18-year-old Americans, meanwhile, text one another under their desks (certain they are sly enough to go unnoticed), check e-mail, decline to take notes, and appear tired and disengaged. There are many distractions and less discipline among American students, as stated in My lazy American students. It can be said that because of the certain aspects of the American culture, American students enjoy communication, they are used to using the technologies that are always near, and studying has to be diverse and interesting. That is why there ca n be seen clear differences between American students and students in other countries. Of course all American students are different, and many of them are talented, hard-working, they listen intently and pay attention to studies. The majority of American students use their knowledge, innovative approaches, which results in a creative work. These peculiarities belong to American students. Although, the creativity without knowledge does not bring any benefits. In 2007 it was reported that eighth graders in even our best-performing states like Massachusetts scored below peers in Singapore, South Korea, and Japan, while students in our worst-performing states like Mississippi were on par with eighth graders in Slovakia, Romania, and Russia., according to the American Institutes for Research. Also, there is a knowledge gap and the lack of the basic knowledge among American students. They prefer to concentrate only on what they are interested in and they do not want to know a little about everything. It can be also said that the time management is considered a problem among American students. They spend a lot of time going somewhere, even late at night. It is the way of life and the aspect of the culture that has to be accepted. Missing studies by different reasons is not a way out, as the best way to study is in the classroom. In 2002, it was found that most 18- to 24-year-olds could not find Afghanistan, Iraq, or Japan on a map, ranking them behind counterparts in Sweden, Great Britain, Canada, Italy, Japan, France, and Germany., according to National Geographic-Roper survey. It is sad that some students are not interested in the outer world, as they are focused on their problems and several topics that they are interested in. According to Kara Miller (2009), success is in the time management and in a globalizing economy, Americans inability to stay focused and work hard could prove to be a serious problem. Working hard is the main principle that has to be present in each culture in each country. In comparison with the American students, it is believed that Korean students make more efforts to study better and better, and finally succeed. Korean students are more responsible in their studies and they are not used to distract on other things. They are used to concentrate on studies and then to do everything else, as this is the rules of the implemented culture. According to South Korean students face long hours of study (2010) , Korean students spend up to 14 hours a day in some form of education, including after school classes, studying with a tutor or taking supplementary courses, such as English, Chinese, Music, and Maths.- Jeonju, South Korea. 24/01/2010. Studying for so long is determined by the effects and the expected outcome in the future, in getting the best possible job and life. Also, Korea has a long cultural tradition that places a strong emphasis on higher education, which contributes to the students international success. A middle school teacher Mr. Bae says that Korea wants to be the first among other countries. From elementary to high school, Korean students spend up to 14 hours a day, including after school classes, studying with a tutor or taking supplementary courses, such as English, Chinese, music, and math at the local neighborhood hogwon., according to South Korean students face long hours of study (2010). As a fact, a Korean students life is dominated by the need to pass an exam to gain entry into a high school and getting a high score to gain admittance into a prestigious university. Korean students have to build character and independence by being responsible for their schools janitorial work, which includes taking out the garbage, sweeping, vacuuming, and cleaning the toilets., according to South Korean students face long hours of study (2010). The considerable influence on Korean students comes from their parents, their culture, traditions, goals in life and the main aims. According to some independent opinions, Korean students study better, as it depends on the importance given to education in general, parental commitment to their childrens education, teachers preparation, and the significance of mathematics for every students successful future., according to Woo Hyung Whang (2011). The culture of Korea values scholarship and Confucianism is also very influential. As well, Parental dedication to childrens education is remarkable in Korea which determines the success of Korean students and their desire to study. Encouragement to study is present in the Korean culture and it is valued very much, as well as the order in everything and true devotion. According to Study compares American students with other countries (2007) , Concern that science and math achievement was not keeping pace with the nations economic competitors had been building even before the most recent Times survey, in which the highest-performing nations were Singapore, Taiwan, South Korea, Hong Kong and Japan. Today the level of competition among the countries is very high, and each country wants to ensure that its educational system is the best, the most effective and the most perspective. Promotion of education is extremely important and despite the cultural differences American and Korean students try to study better, to set goals and to succeed. It can be said that the culture has a considerable influence on studies, on students relation to them, and to the perspectives that may appear, as stated in Korean students flocking to Canada to study English (2006). I presume that it is important to respect both Korean and American culture, to use different approaches to educate students and to use various ways of evaluation of Korean and American students. It is important to create comfortable conditions for students and teachers, in order to provide a better educational process and to renew the intentions and desire of students to study more and better. Studying is important and cultural differences do not have to influence the educational process. All in all, it can be said that there have to be used different approaches according to cultural differences and peculiarities. Korean students should not be evaluated using the same way with American students. It is important to ensure that the evaluation will be different and that there will be used different approaches, more suitable for Koreans and American students. In some aspects there can be found considerable differences in the culture and the philosophy of the two countries, but the aim is the one- to study better.

Friday, September 20, 2019

Management Respiratory Distress Syndrome Infants Health And Social Care Essay

Management Respiratory Distress Syndrome Infants Health And Social Care Essay Respiratory distress syndrome (RDS) is one of the most common consequences of prematurity and a leading cause of neonatal mortality and morbidity as a result of immature lungs. RDS particularly affects neonates born before 32 weeks of gestational age but is also recognised in babies with delayed lung maturation of different aetiology i.e. maternal diabetes. Since its initial recognition there have been vast advances in understating the pathology and management of this complex syndrome. However, in order to understand the pathology behind RDS it is imperative to obtain a good foundation of normal lung maturation and physiological changes that occur in the respiratory system during the transition from fetal to neonatal life. Physiological Development and Function of the lungs During intrauterine growth, fetal lung development begins as early as 3 weeks and progresses until 2-3 years. Conventionally it is divided into 5 stages; embryonic, pseudoglandular, canalicular, saccular and finally alveolar1 (Table 1). During the embryonic stage, the lungs develop from the fetal ectoderm to form the trachea, the main bronchi, the five lobes of the lung and the major blood vessels that connect the fetal lungs to the heart; the pulmonary arteries. This is followed by the pseudo glandular stage which results in the formation of the terminal bronchioles and associated primitive alveoli. These then further divide in the Canalicular stage to form the primary alveoli and subsequently the alveolar capillary barrier. This stage also comprises the differentiation of Type 1 and 2 pneumocytes which will later go on to produce surfactant. Thus babies born after 24 weeks, have a chance of survival as the platform for basic gas exchange has begun to develop. During the saccular st age there is further differentiation of type 1 and type 2 pneumocytes and the walls of the airways, in particular the alveoli, thin to enlarge the surface area present for gaseous exchange. This is followed by the alveolar stage which occurs through the transition form fetal to neonatal life up until 2-3 years. The hallmark of this stage is alveolar formation and multiplication to augment the surface area available for gas exchange to meet the increasing respiratory demands as the infant grows. Stage Time period Structural Development Embryonic 0-7 weeks Trachea, main bronchi and five lobes of the lungs develop from the fetal ectoderm. Pulmonary arteries form and connect to heart. Pseudoglandular 7-17 weeks Formation of terminal bronchioles and alveoli Canalicular 17-27 weeks Formation of alveoli-capillary barrier and differentiation of type I and II pneumocytes Saccular 28-36 weeks Walls of airway thin for efficacious gas exchange Alveolar 36 weeks -2 years Alveolar multiplication Table 1: Stages of Lung Development Once the pulmonary epithelium develops, it begins to secret fluid into fetal lungs, the volume and rate of which is imperative for normal lung growth. Another important factor essential for normal lung development and function is the production of surfactant. At about 24 weeks of gestation the enzymes and lamellar bodies required for surfactant production and storage begin to appear 3. Thus a normal fetus age is not ready to be delivered at this stage due to surfactant deficiency. As type II pneumocytes mature between 32-36 weeks, surfactant production increases and it is stored in the lamellar bodies of these cells. Surfactant is a complex mixture of phospholipids, neutral lipids and proteins 1, 4 that has a fundamental role in maintaining the alveolar-capillary interface and reducing surface tension. It is secreted as a thin film at the liquid-air barriers to facilitate alveolar expansion and prevent end-expiratory collapse of small alveoli, especially at low alveolar volumes. A key event in the development of the lungs is the establishment of spontaneous breathing post-delivery. Prior to delivery the fetal lungs decrease lung fluid production and as the lungs mature there is simultaneous maturation of the lung lymphatic system. During labour the mechanical compression of the fetal chest forces about 1/3 of this lung fluid thus preparing the fetus for spontaneous ventilation. This will require several stimuli; including hypoxia, hypercrabia and acidosis as a results of labour5 and hypothermia and tactile stimulation. Furthermore the stress of labour stimulates chemo-receptors in the fetal aorta and carotids to trigger the respiratory centre in the medulla to commence breathing. As the fetus emerges from the birthing canal, the fetal chest re-expands creating negative airway pressure which subsequently draws air into the lungs. This again forces the lung fluid out of the alveoli and allows for adequate lung expansion. As the newborn cries there is further e xpansion and lung aeration generating positive intrathoracic pressure which maintains alveolar patency and forces any remaining fluid into the lymphatic circulation. As the neonate adapts to extra-uterine life, the normal muscles of respiration work to maintain breathing (Figure 1). In order to inhale, the diaphragm and external intercostals muscles contract to increase the size of the thorax. This generates negative air pressure in the pleura and lowers the air pressure in the lungs so that the gradient between atmospheric air and alveolar air causes air to enter into the lung of the neonate. As the neonate inhales, the elastic recoil force of the lung increases. Once inspiration ceases, the elastic recoil force of the lung causes expiration. The diaphragm and external intercostals muscles relax, the thorax returns to its pre-inspiratory volume resulting in an increase in intra-thoracic pressure. This pressure is now greater than atmospheric pressure and air moves out of the lungs producing exhalation. Figure 1: The Mechanics of breathing6 For most neonates, this transition from fetal to extra-uterine life is uneventful and completed during the first 24 hours of life. The neonate is able to establish good lung function, maintain cardiac output and thermoregulate. However, for a certain population of neonates, usually those that are born early and thus called preterm, this transition is less smooth and it is these babies that will require the support and care of the whole paediatric department. Respiratory Distress Syndrome Respiratory distress syndrome (RDS) is the most prevalent disorder of prematurity and despite a better understanding of its aetiology and pathology, RDS still accounts for significant neonatal mortality and morbidity. The incidence RDS is inversely proportional to gestational age2 such that it decreases with advancing gestational age, from about 60-80% in babies born at 26-28 weeks, to about 15-30% in babies born at 32-36 weeks 1. Risk factors for developing RDS are summarised in Table 2 and include maternal illness, complications during pregnancy and labour and neonatal complications Table 2: Risk Factors for RDS1 Respiratory distress presents early in post-natal life particularly during the phase of transition from fetal to extra-uterine life. These babies will present with signs of grunting, cyanosis, nasal flaring, intercostal and subcostal recession, increased respiratory effort, and less commonly apnoeic episodes and circulatory failure. The severity of symptoms experienced are related to the pathology of disease and it is important to identify babies at greatest risk and commence management early in order to prevent respiratory complications such as chronic lung disease (previously called bronchopulmonary dysplasia), pulmonary hypertension and in adverse cases respiratory failure and even death. Identifying normal transition and respiratory distress is largely based on evaluating the risk factors for RDS, assessing the severity of symptoms and close neonatal observation if in doubt. Babies that are born close to term or those via caesarean section may display a difficult albeit a normal transition. These babies present with transient tachypnoea of the newborn in the first few hours with respiratory rates of about 100 breaths per minute and increased oxygen requirements. Symptoms are short lived, self limiting in most cases and usually relived by oxygen. Neonates who suffer from RDS will present with worsening symptoms of longer duration, respiratory rates of 120 and increased respiratory effort with a longer requirement for oxygen. Recovery if plausible usually begins after 72 hours and is associated with decreased oxygen requirements and better functional residual capacity. Pathophysiology of Respiratory Distress Syndrome Since its initial recognition, more than 30-40 years ago, much has been elucidated about the pathophysiology of this complex syndrome. In the premature neonate, the structurally immature and surfactant deficient lung is unable to maintain the basic lung mechanics required for adequate ventilation. As aforementioned lung mechanics rely on surfactant production, alveolar multiplication and maturity for effective gas exchange, chest wall elasticity and a functionally developed diaphragm. It is therefore evident that premature neonate who lack surfactant and have structurally immature lungs will develop RDS, atelectasis and abnormal lung function. In these neonates the essential first breaths are followed by a secondary pathological cascade characterised by tissue damage, protein leakage into the alveolar space and inflammation, which may resolve or progress to BDP or chronic lung disease of prematurity (CLD)7. In neonates with RDS, end-expiration results in the collapse of alveoli due to surfactant deficiency and a subsequent reduction in the functional residual capacity (FRC). The FRC is the volume available for gaseous exchange i.e the volume of gas left in the lungs after exhalation. It is determined by an intricate balance between the collapsing and expanding forces of the chest wall and lungs7. An ideal FRC enables the best possible lung mechanics, efficient ventilation and gaseous exchange. As the FRC is reduced at end-expiration due to alveolar collapse due to high surface tension, the pressure that will be required to re-inflate the already immature lungs is increased. This in turn increases the respiratory effort needed for adequate gas exchange which presents clinically as increased respiratory rate and subcostal/intercostal recession. Moreover reaching an optimal FRC may be further impeded by both surfactant deficiency and by the preterm infants impaired ability to clear fetal lung fluid. Radiographically a chest x-ray will show the characteristic ground-glass appearance with diminished lung volumes and the cardinal features of respiratory stress, tachypnoea, nasal flaring, intercostals recession, subcostal recession, increased breathing effort and grunting will begin to manifest early on. Despite this effort to breathe, alveolar ventilation remains poor. As these areas are receiving an adequate blood supply this produces a ventilation/perfusion mismatch resulting in right to left intrapulmonary shunting1. The lungs are unable to maintain good gas exchange and blood oxygen saturation and the level of carbon dioxide begins to increase resulting in respiratory acidosis, hypoxaemia and hypercarbia. The neonate further struggles to breath and attempts to generate higher negative pleural pressures to ventilate the lungs. The ensuing acidosis further diminishes surfactant production and neonates deteriorate rapidly as blood oxygen saturations plummet. The natural progression of the disease if left untreated will lead to pulmonary oedema, right-sided heart-failure and ultimately the most devastating outcome, neonatal death. Therefore the management of these neonates requires an aggressive multi-disciplinary team approach based on the pathology of these aforementioned homeostatic mechanisms. Alongside this the basic principles of neonatology; thermoregulation, nutritional support, efficacious cardiovascular support and infection control, are all fundamental in achieving the best therapeutic goal. Ultimately the aim is to provide adequate ventilatory support, allow the lungs to heal, impede further pulmonary injury, correct hypoxaemia and acidosis and above all to keep the neonate alive. Management of RDS As aforementioned the aim of treatment is to promote lung healing and reduce further pulmonary insults. We have already established that with increasing gestational age, particularly post-32 weeks, the infant will require less aid to help it cope with the transition from fetal to neonatal life. However, before 32-weeks there is an increased propensity to develop RDS and as the neonate is unable to cope, some form of respiratory support is required. Over the past 40 years there have been numerous management therapies including ventilatory support, surfactant therapy, nitric oxide therapy and supportive therapeutics strategies amongst others. The mainstay of treatment today remains supportive and involves the use of antenatal steroids, surfactant replacement therapy, continuous positive airway pressure and mechanical ventilation, which all aim to address the pulmonary insufficiency that manifest in these individuals Antenatal Glucocorticoids Glucocorticoid receptors are expressed in the fetal lung at early gestation and as the fetus grows stimulate surfactant production post-32 weeks. Alongside receptor expression there is an increase in fetal cortisol levels at late gestation9, which coincides with lung maturation, type II pneumocyte differentiation, surfactant synthesis as well as alveolar thinning. If birth occurs before this increase in serum cortisol, the pulmonary system has not matured adequately and therefore there is an increased propensity to develop RDS. Thus a single dose of glucocorticoids such as dexamethasone or betamethasone in the antenatal period promotes lung maturation. One of the first published reviews that showed the efficacy of antenatal steroids in preterm labour was produced by Crowley in 19958. Crowley showed that steroids given in preterm labour were effective in preventing RDS and improving neonatal mortality rates. Since then several randomised controlled clinical trials have evaluated the efficacy of steroids in reducing RDS. A recent Cochrane review of 21 trials assessed the effects of antenatal corticosteroids, given to women expected to go into preterm labour, on fetal/neonatal mortality and morbidity8. The authors concluded that a single dose of antenatal steroids promoted fetal lung maturation thereby reducing the risk of RDS and the need for assisted respiratory management. The mechanisms by which glucocorticoids are thought to exert their efficacy are described below. Firstly, glucocorticoids stimulate phospholipid production. Phospholipids are a major component of endogenous surfactant and as a result augment surfactant synthesis in the biochemically immature and surfactant deficient lung 9, although the exact mechanisms by which this occurs remains to be elucidated. Secondly glucocorticoids enhance lung maturation and development. As aforementioned, in order to produce surfactant, fetal lungs must produce type II pneumocytes which will then generate lamellar bodies in which surfactant is stored. Glucocorticoids enhance this process, promoting pulmonary epithelial cell maturity and differentiation into type II pneumocytes9. Furthermore glucocorticoids cause a decrease in pulmonary interstitial tissue thereby decreasing alveolar wall thickness. A thin alveolar wall thickness facilitates efficacious gaseous exchange and will therefore assist ventilation and oxygenation of the neonate once born thus decreasing the chances of developing RDS. Another known benefit of antenatal glucocorticoids is found in reducing oxidative stress on the immature lung and prevention of pulmonary oedema9. This accumulative evidence suggests that glucocorticoids are essential for normal pulmonary development and giving a single dose to mothers at risk of preterm birth may substantially decrease the chances of the infant developing RDS. Surfactant Therapy As discussed before, endogenous surfactant has a fundamental role in maintaining the alveolar-capillary interface in order to prevent end-expiratory alveolar collapse. This is achieved by thin spread of surfactant around the alveoli which ultimately acts to reduce surface tension. The most important component of surfactant which achieves this fundamental function is a phospholipid called dipalmitoylated phopshatidylcholine (DPPC)11. DPPC also stabilises the alveoli at end expiration, further preventing alveolar collapse. Alongside DPPC the synergistic actions of surfactant proteins (SP) SP-B and SP-C also lower surface tension11. Thus a deficiency in surfactant will cause alveolar collapse, decrease pulmonary compliance, increased pulmonary vascular resistance and produce ventilation-perfusion mismatch. Hence the aim of exogenous surfactant therapy is to reverse this pathological cascade and ultimately prevent alveolar collapse thereby limiting pulmonary damage and improving ventilat ion. Since the first clinical trial assessing the use of surfactant in managing neonatal RDS by Fujiwara in the 1980s10, our understanding of the composition, structure and function of surfactant has progressed vastly. In this uncontrolled trial the chest x-rays of 10 babies diagnosed with RDS, both clinically and radiologically, showed significant improvement after exogenous modified bovine surfactant was administered with a decreased requirement for ventilation. Since then several randomised controlled trials12 have shown that surfactant therapy, alongside antenatal steroids and ventilation continues to improve neonatal morbidity and mortality. Both natural (derived from an animal source) and synthetic (manufactured chemically) surfactants are available to use in managing RDS. Meta-analysis of trials comparing the two types of surfactant have shown that natural surfactants show a more rapid response in improved lung compliance and oxygenation12 thereby reducing neonatal mortality. Furthermore natural surfactants are less sensitive to inhibition by accumulative products of lung injury such as serum proteins. Surfactants need direct delivery to lungs and usually require intubation with short periods of assisted ventilation. Traditionally two therapeutic approaches have been established in managing RDs with surfactant. The first adopts the use of surfactant prophylactically, with surfactant given immediately after birth to enable the neonate to cope with extra-uterine life. The obvious benefit of this approach is that surfactant is administered to the baby before severe RDS develops resulting in long-term pulmonary sequelae for the neonate. However this technique is invasive, as surfactant administration requires endotracheal intubation, it is expensive and furthermore it may result in the unnecessary treatment of neonates. Moreover poor intubation with failed attempts and prolonged apnoeic episodes may further damage the lungs resulting in CLD. Despite this, there is a strong body of evidence for prophylactic use of surfactant and current guidelines state that all preterm babies born befo re 27 weeks of gestation, who have not been given antenatal steroids should be intubated and given surfactant at birth7. The second therapeutic approach evaluates the role of surfactant in rescue treatment used in neonates with an established diagnosis of RDS requiring ventilation and oxygen. The advantages of rescue treatment include that it is reserved for neonates in whom RDS is confirmed and it may decrease the morbidity associated with unnecessary intubation. The obvious disadvantage is that delay in surfactant delivery may allow for irreversible lung injury to develop with decreased efficacy of surfactant administration12. Several studies have aimed to clarify the issue between prophylactic and rescue surfactant treatment. A randomised trial by Rojas et al. showed the benefits of surfactant delivery within 1h of birth in neonates born between 27-31 weeks14 with an established diagnosis of RDS who were treated with continuous positive airway pressure soon after birth. 279 infants were randomly assigned either to the treatment group (intubation, very early surfactant, extubation, and nasal continuous positive airway pressure) or the control group (nasal continuous airway pressure alone). The results of this study demonstrated that infants in the treatment group i.e. those treated with surfactant, showed a decreased need for mechanical ventilation with a decrease in the incidence of CLD and pneumothoraces. Neonatal mortality rates were similar between both groups. A meta-analysis by Soll and Morley compared the effects of prophylactic surfactant to surfactant treatment of established respiratory distress syndrome (i.e. rescue treatment) in preterm infants33. The authors analysed eight studies comparing the use of prophylactic and rescue surfactant treatment and concluded that the majority of the evidence demonstrated a decrease in the incidence of RDS when surfactant was given prophylactically. Moreover the meta-analysis showed that infants treated with prophylactic surfactant had a better clinical outcome with a reported decrease in the risk of pneumothorax, pulmonary interstitial emphysema, CLD and mortality33. As a result of such studies most neonatal units continue to practice delivery of surfactant prophylactically in preterm babies at high risk of RDS. However, some literature still debates whether there are any real advantages of prophylactic surfactant over rescue treatment. What is evident is that surfactant therapy should play a fundamental role in the management of RDS. Future trials will need to further assess the indications for surfactant therapy in treating neonatal RDS and perhaps in the management of other pulmonary insufficiency disorders that affect the neonate. Although much remains to be elucidated about the complex pulmonary surfactant system, since its introduction 25 years ago, surfactant therapy has been at the forefront of reducing RDS and its role in decreasing neonatal mortality and morbidity cannot be disputed. Mechanical ventilation Mechanical ventilations is one of the cornerstones of neonatal intensive care units and regardless of the modality used, the primary function is to maintain adequate oxygenation and ventilation. The goals of mechanical ventilation are: to establish efficacious gaseous exchange to limit pulmonary insult and CLD to reduce the respiratory effort and work of breathing of the patient To achieve these basic goals several techniques, devices and therapeutic options are available to the neonatologist that can be either invasive or non-invasive. Continuous Positive Airway Pressure The use of CPAP; continuous positive airway pressure, in the treatment of RDS was first described in the 1970s and has since been identified as a important management strategy. CPAP applies positive end expiratory pressure (PEEP) to the alveoli throughout inspiration and expiration so that the alveoli remain inflated thereby preventing collapse. The pressure required to re-inflate the lungs is reduced as partially inflated alveoli are easily to inflate than completely collapsed ones. Animal studies with premature lambs have shown the benefits of nasal CPAP over mechanical ventilation. CPAP acts to lower the markers for CLD for example granulocytes, and markers of white cell activation, increases the amount of surfactant available, improves oxygenation and lastly corrects ventilation/perfusion mismatching2, 15. Moreover CPAP produces a more regulated pattern of breathing in neonates by stabilising the chest wall and reducing thoracic distortion16. Like surfactant therapy there are two ways in which CPAP can be administered. The first method, InSUrE: intubation, surfactant and extubation, adopts a brief intubation to administer surfactant and extubation to CPAP approach and the second is the Columbia method in which babies are started on CPAP in the delivery room and are only mechanically ventilated, and intubated if the need for surfactant is established. Several studies have shown the benefit of the first approach. A study by Verder et al. randomised 68 neonates with moderate to severe RDS; 35 infants were randomised to surfactant therapy following a short period of intubation and then extubation to CPAP and 33 neonates were randomised to nasal CPAP alone. The results of this study showed that infants in the earlier group had a reduced need for ventilation; 21% in comparison to 63% in the second group16,17. Another similar trial by Haberman et al. assessed the use of surfactant with early extuabtion to CPAP and subsequently the results showed a decreased need and duration for mechanical ventilation12. Furthermore a recent Cochrane review of six studies using the InSuRE method showed that neonates with RDS treated with early surfactant therapy followed by nasal CPAP, were less likely to need mechanical ventilation and develop air leaks in comparison to neonates that were treated with the Columbia approach (i.e. early CPAP therapy foll owed by surfactant if needed)17, 18. A more recent review by the same authors further confirmed the findings of the initial review and the relative risk for developing CLD was 0.51 (95% CI 0.26-0.99) with early surfactant treatment and nasal CPAP when comparing the two methods18. The Columbia method requires the stabilisation of neonates with CPAP in the delivery room with intubation and surfactant therapy used as necessitated. This approach was adopted when retrospectives studies done by Avery et al. and later Van Marter et al. evaluated the clinical outcomes in multiple neonatal units across the US2. In both cases a lower incidence of CLD was observed in the Columbia University Hospital which adopted CPAP as a primary treatment strategy as opposed to intubation and mechanical ventilation like other units. Leading on from this Ammari et al.. evaluated the Columbia method recently. The outcomes of 261 neonates with birth weight So far the evidence base for the Columbia method has been derived from retrospective cohort studies with a lacking in RCTS and therefore a lack of stronger evidence. One RCT that had aimed to evaluate the Columbia method was the recent COIN trial by Morley. This study evaluated whether the incidence of death or BPD would be reduced by CPAP rather than intubation and ventilation shortly after birth13. 610 neonates born between 25-28 weeks were randomised to CPAP or intubation and ventilation at 5minutes after birth and surfactant was administered at the neonatologists discretion. The results of the study demonstrated that at 28 days of gestation, infants in the CPAP group had a decreased need for supplemental oxygen and fewer deaths2,13. However worrying results from this study were that approximately 46% of babies in the CPAP group went onto require intubation and had a higher rate of pneumothoraces13. There are few randomised control trials assessing the benefit of CPAP alone in managing RDS and the results of the Columbia Hospital study have been irreproducible in other centres. The mainstream use of CPAP for managing RDS remains to start CPAP in the delivery room, after intubation for surfactant treatment. There is not enough evidence to show that CPAP alone can prevent RDS and associated complications in comparison with invasive ventilation. The evidence does suggest that there is a decrease in complications with surfactant therapy and CPAP but the relationship with CLD is less transparent. At present there are two RCTs ongoing that may provide further insight into the role of CPAP in RDS when complete. The first trial is the SUPPORT study, which is randomising infants between 24-27 weeks to CPAP beginning in the delivery room with stringent criteria for subsequent intubation, or intubation with surfactant treatment within 1 h of birth with continuing mechanical ventilation2. The second is the trial by the Vermont-Oxford Network in which infants born at 26-29 weeks gestation will be randomised after 6 days into one of three groups; (1) intubation, early prophylactic surfactant, and subsequent stabilisation on mechanical ventilation; (2) intubation, early prophylactic surfactant, and rapid extubation to CPAP; and lastly (3) early stabilisation with nasal CPAP, with selective intubation and surfactant administration according to clinical guidelines2. The immediate management of the RDS neonate with CPAP remains controversial and maybe the results of these ongoing RCTS wil l provide invaluable answers to the many uncertainties surrounding this device. Nasal intermittent positive pressure ventilation Another relatively recent development in non-invasive ventilation that has evolved from NICU ventilator machines and CPAP devices is the use of NIPPV for managing RDS. Sometimes called BiPAP (for bi-level positive airway pressure), this form of non-invasive ventilation is able to provide two levels of airway pressure, without the need for intubation. BiPAP maintains positive pressure throughout respiration but with a slightly higher pressure during inspiration. By doing so BiPAP/NIPPV is able to assist neonatal breathing by: reducing the work of breathing improving tidal volume increasing blood oxygen saturation and increasing removal of CO2 thereby limiting hypoxaemia and respiratory acidosis. As the neonate inhales, the NIPPV device generates a positive pressure thereby assisting the neonates spontaneous breath and providing ventilatory support. This is at a slightly higher positive pressure. As the neonate begins to exhale, the pressure drops, but a positive airway pressure remains in the lungs to prevent alveolar collapse and thus increase gaseous exchange. NIPPV may be a potential beneficial treatment for the management of babies with RDS and has been used in NICUs since the 1980s. Recently multiple studies have aimed to evaluate the efficacy of NIPPV in stabilising neonates. A randomised controlled prospective study by Kulgeman et al.. found that NIPPV was more successful than NCPAP in the initial treatment of RDs in preterm infants19. Kulgeman and his colleagues randomised infants A further study by Sai and colleagues also established the advantages of NIPPV over CPAP in managing RDs and reducing the need for mechanical ventilation and intubation in preterm infants. In their study 76 neonates between 28-34 weeks gestation with RDs at 6h of birth were randomised either to early NIPPV (37 neonates) or early CPAP (39 neonates) after surfactant use20. Firstly they documented that the failure rate with NIPPV was less in comparison to the CPAP group (p

Thursday, September 19, 2019

Macbeth - A Tragic Hero :: essays research papers

William Shakespeare’s play Macbeth, written in the 1600’s is a perfect example of Shakespeare’s ability to manipulate his audience through creating a tragic hero. A tragic hero who, because of a flaw, tumbles from a well-respected hero to a cowardless murderer. It is through Shakespeare’s manipulation of figurative language, dramatic conventions and social expectations of the seventeenth century, do the audience witness the demise of this mixed up man. Macbeth’s persona of the tragic hero is enhanced even more when the characters around him influence his decisions, creating mayhem inside his mind and disorder throughout Scotland. Shakespeare positions his audience to respond to the central theme: the struggle between good and evil, by illustrating to the audience his weaknesses, which through the guidance of the supernatural, leads to murder and mayhem and eventually madness. It is this influence of the supernatural that leads to Macbeth’s t ragic persona and in turn his physical and mental destruction. Shakespeare utilises these techniques to embody in Macbeth characteristics indicative of that of a seventeenth century tragic hero. Aristotle described the Greek image of the tragic hero as one who takes: part in a fictional account of a set of events that is serious, complete and of a certain magnitude.† (The Poetics) Macbeth conforms to the image of the tragic hero by possessing a flaw and dying because if it. His flaw of being led too easily is evident through the actions of characters who influence Macbeth. Macbeth is involved in a story intertwined with evil, disorder, conflict and failure; all resulting finally in his death. Part of being a tragic hero is possessing a flaw. A flaw which will inevitably lead to self-destruction; the fall of the tragic hero. In the play, the central protagonist Macbeth, is confronted with the supernatural and the prophesy of becoming king. He cannot help but want this position, as this flaw also includes his weakness through over ambition. It is generally said that those possessing a flaw will die. The first Thane of Cawdor was a traitor, Duncan was too trusting, Banquo did not act on the knowledge he had about Macbeth’s murders, Lady Macbeth helped plot the murder of Duncan, and Macbeth destroyed the natural order and harmony of the time. All of these d eaths are a result of Macbeth’s over ambition to become king, fuelled by the prophecies of the evil witches. Like Macbeth, a tragic hero has choices, a conscience of right from wrong and in the end must die, because to live would create mayhem and a feeling that his actions were justified.

Wednesday, September 18, 2019

Internet Taxation Essay -- Internet Tax Taxing Essays

Internet Taxation The passage of the Internet Tax Freedom Act, on October 21, 1998 there has been an intense debate on whether to tax or not to tax Internet purchases. The conservative side is opposed to Internet taxation saying that it is too costly to collect tax on Internet purchases. They also believe that since Internet retailers do not have any of their operations in all the states, not every state should receive the sales tax made on the purchase. On the other hand, the liberal believe that taxation of the Internet should be lawful because states are losing valuable tax bases to Internet purchases. They believe that at current rates of online shopping, states are losing millions of dollars annually that are used for public roads, police protection, and education. Both sides of the Internet taxation argument use logos and ethos appeals. Logos appeals are the main form of argument for both sides. Plenty of examples and statistics are used to support the logos argument. Ethos appeals are not as prevalent as logos, but are enter strung throughout the articles to support both sides. Pathos appeals are almost non-existent in any articles found, so they are not a main contributing factor in the overall argument on Internet taxation. In the Issues & Controversies section of Clemson Universities Expanded Academic Search the article, â€Å"Internet Taxation,† both the pros and cons concerning Internet taxation are mentioned to establish both views concerning the issue facing the United States people. The conservative or con side on taxes mainly uses logos argument to make their point. Supports of the tax free Internet say that because of the way transactions are carried out on the web, electronic sales are vulnerabl... ...o adopt a unified sales tax for Internet purchases. They are a liberal group for Internet taxation, which recently got shot down with the onset of the extended Internet Tax Freedom Act. The coalition is not currently trying to persuade e-tailers to join their position on Internet taxation. Big names such as Amazon.com have not joined the talks for good reason. Online retailers do not want states to adopt a plan to implement taxes online since it would threaten the tax-free shopping advantage that these online retailers enjoy. Even with the onset of new rulings for a tax-free Internet there has not been a complete loss for the coalitions efforts. In a 1992 Supreme Court ruling states that e-tailers must collect sales tax in the states in which they have a physical presence. All in all efforts for both sides have resulted in a partial tax and tax-free Internet.

Tuesday, September 17, 2019

The overview of Last In/First Out and First In/Last Ou

The overview of Last In/First Out and First In/Last Out is now completed for the date and time of your choice to discuss the company matters. The information from last month is was completed at the end of the month and the present is kept current on a daily base as management needs to be up to date of the inventory and financial levels of the company. Reducing federal and state income corporate taxes are important as this may allow the company to see a decrease in expenses over the time. Looking at the expenses of the company and viewing the incomes of the employees will allow the company to make the decision as to Last In/First Out or First In/Last Out to save the company finances. Although looking at the inventory will allow the management to view the Last In/First Out and First In/Last Out as to the timing of the inventory growth. Using First In/Last Out will allow the company to still grow as the inventory increases and the company will still profit. Using Last In/First Out will allow the company to be at a stand point and no increases are made. Understanding the decision that is made must be final, this information will be viewed and continued to be up to date for any financial issues that may arise before and after the meeting and decisions are made. By looking at the short and long term on Cost of Goods Sold this will allow you to make the judgment of the Last In/First Out and First In/Last Out and it shows the profit for the company in the past and allow you to predict the future. Good luck with your decision and I stand by you on the choice that is made.

Monday, September 16, 2019

Cultural Oppression Essay

Both African Americans and Asian Americans have suffered racial discrimination, slavery, persecution, difficulty in receiving citizenship even though their children were born in the United States and challenges in demonstrating their cultural identity. They experienced difficulty in classifying themselves as purely American because of their outward appearance. Moreover, they always tend to feel insulted that white Americans will always judge them by stereotypes, not by what they really are. African Americans have suffered dual consciousness in the United States, always struggling to receive social and economic equality, both as a Negro and an American. Although political equality has been granted to African Americans, they still suffered inequality in terms of achieving social and economic wealth. The effects of cultural oppression on African Americans have put them at high probability of suffering continued hindrances to achieve societal empowerment and affirmation. However, the richness of African cultures that place importance on collective lifestyle has helped African Americans to be accepted in the United States. Asian Americans were pressured to learn how they could assimilate themselves into different cultural society in the country. The cultural oppression suffered by Asian Americans has helped them to establish their own community in order for them to become self-sufficient. The impact of the Eastern philosophies, Buddhism, Taoism, and Confucianism, on Asian culture has helped families to become paternally oriented and hierarchical. The notable reason why some Asians have the tendency to avoid debate and discussion or to appear indecisive is because of these philosophies that teach them principles of harmony, balance and peace. This Asian culture has provided them to act in a positive way and to learn the importance of having self-knowledge about how others behave towards them. Reference Information on Specific Cultural Groups. Retrieved April 17, 2009, from http://education. byu. edu/diversity/culture. html.

Sunday, September 15, 2019

How Far The Australia’s Legal, Political And Educational Structures Are Modeled On British Institutions Essay

Australia was colonized by British and was granted independence in 1901. The six colonies which had been formerly inhabited by the British during colonization became the six states in the federal government that Australia assumed. Most of the legal, political and education systems borrowed a lot from British institutions, although Australia preferred to borrow the federal system from America (State University, 2009).   Some of the powers that had been held by the states were volunteered progressively and when the twentieth century came to close, the federal government was responsible in running Australia. How Far the Australia’s Legal, Political and Educational Structures Are Modeled On British Institution The major institutes in Australia such as bureaucracy, education and the language that is commonly used there have a British line modeling. Some of The universities that were in Australia in the 1920s boasted of being as old as three- quarter century. It was quite evident that there was no one teaching economics until 1913. The professor who was teaching history or philosophy gave a single or double lecture on the theory of economics in a week. Due to the extensive work load, economics experienced a lot of negligence something that profoundly shocked the Americans (Heaton, 2008). Most universities in Australia had borrowed a lot of British ideas in their modeling and with special preference of Cambridge and Oxford which concentrated in technical training, back in 1920s. Economic science had minimal teaching in Britain until recently and Australia gave little attention as it held the British system highly. Mathematics, philosophy, classics and literature that were commonly offered in most universities in Britain were accorded a lot of respect by the Australians who also offered them in their universities. There was a lot of attention in offering of law, medicine and engineering which were traditional courses offered in universities of Britain. The state established most universities in Australia, and the largest proportion of revenue was drawn from public coffers and this takes place up to date (Heaton, 2008). Most endowments that were private contributed minimally to the development of universities in Australia unlike in America. These private endowments invested half the revenue that the government invested in public institutions. Money from the public was unconditionally granted by the government which made no attempt to seriously control policies and teaching. The universities were dependent on the state, similar to universities in Britain. The first universities in Australia were established with the aim of meeting the standards that stressed their capability of meeting the values and norms of the models of British universities which were considered to be the most appropriate (University of Western Australia, 2003. These models that were adopted have made it impossible for newer universities to adopt any other system as a powerful effect has been exerted by the already existing universities. The government draws a lot of security from scientific interests than culture and education is seen more of an instrument than experience (State University 2009). The community also perceives the university to be a place where it is served through the training of lawyers, engineers, dentists, teachers and doctors and thus these traditional courses continue holding a lot of attention. Specialization is very common in most of the Australian universities and once a student goes to a specific department, they will be ignorant on other departments. This has resulted to the graduates being more professionalized than educated. This phenomenon is common in most prestigious universities in Britain. America has the most diversified university programs and there is a call for conformity of Australian universities by the people. Australian law is comprised of the common law, (which derives its basis from the common law of Britain), the constitution and federal laws passed by parliament. The states within Australia exercise their own governing over the court systems and parliaments which are present in each. The systems of government and law that are currently existent in Australia have their legal dependence and validity on the British statutes (University of Western Australia, 2003)    One such statute is the Act of 1900 known as Commonwealth of Constitution of Australia. The characters of legal institutions and Austrian law traditions have a monoculture characteristic. This reflects an origin which is English in nature. The Aborigines who were the natives of Australia were completely ignored by the British as they were too native and the Britons completely disregarded any laws that were in place, but instead subjected them to the England laws (Aroney 2007, p. 8). Recently, Howard made the same maneuver in 2007, by initiating an intervention of communities of the Aborigines who live in the territory that lies in the North of Australia. The forces of the military were mobilized and the government granted them power to directly exercise control over the communities which were targeted. This was to last for five years and this move is no different from what the British did when they first arrived in Australia.   The constitution protects Howard’s maneuvers as the state government can override the government authority in the Northern territory (Stringer 2007, p. 30). This law is still present in the constitution which gives the government the power to constitutionally usurp territorial governments’ sovereignty.   Howard is doing what the British did to the native aborigines since this intervention has been viewed as contravening the human rights due to its discriminatory nature. Howard claims that he is saving the aboriginal children from being sexually abused by the whites in Australia (Stringer 2007,   32). It is evident that the constitution of Australia is still embedded on the Common Wealth Constitution by the British and nothing has been done to include the native Aborigines in the constitution.   Ã‚  The system of court that is present has still borrowed a lot of modeling from the English system (Goldring, 2003).     Ã‚  The high court is the final appeal court and also deals with constitution matters. The basis of the constitution of Australia is the commonwealth constitution that was enacted in 1900 and this statute was used until 1942. The independence of the legislature was enacted in 1986 in Australia. This was a symbol of its freedom from Britain. Until 1990, Australia held the status of constitutional monarchy something it had inherited from Britain. Although there are supreme courts in all states, the high court was established to ensure the uniformity of the common law. The common law is inherent of the common law in Britain (Edwiyna 2008, p. 230). The premier in the UK is an enviable character who enjoys a lot of executive powers that the presidents of America have no access to. This power is similar to what the premier in Australia enjoys a clear picture that Australia adopted the same political arrangement as Britain which had formerly colonized it (Bennister 2007, p. 335). Both the premiership in Australia exhibit a lot of similarities as the there is a lot of capacity and influence from the premier. There are a lot of constraints in the institutional that are discrete, but the capacity of resources is easy to identify. Both of these premiers are stretching the institution through growth in the office of the leaders, policy advice which is bold and centralized and the ministerial adviser’s functions and roles have been strengthened. These new structures, practices and process are entrenched in the political systems of both the premiers and this is attributed to the practice of their executive powers (Bennister 2007, p. 330). Australia adopted the office of the premier with executive powers like Britain who can make decisions that are hardly challenged. Conclusion Australia, which was a British colony, has borrowed so much from Britain in terms of education, legal and political system. Most of its oldest universities were modeled from the famous British universities such as Cambridge and Oxford. There was a perception that the technical courses offered in these reputable institutions should be taken as the guidelines in the universities in Australia. This has made most private investors to shy away from establishing more universities and by 2007; there were only two private universities out of the 39 that were present in the country.   There has been an outcry for the education system to be diversified to conform to that of American universities that are seen as more appropriate. The constitution that borrowed a lot from the Commonwealth Act needs some of the statutes to be reviewed to conform to the modern times. The Act that gives the government permission to usurp Northern territories sovereignty sounds so colonist and it should be reviewed to protect the Aboriginal communities. It is the high time that Australia reviewed its own constitution to include everyone and get rid of some of the statutes that were present during colonialism. From this review, it is clear that most Australian systems are modeled on British institutions. Bibliography: Aroney, N 2007, Comparative law in Australian constitutional jurisprudence: University of Queensland law journal, University of Queensland, Vol. 26(2) pp 8 Bennister, M 2007, Tony Blair and John Howard: Comparative Predominance and ‘Institution Stretch’ in the UK and Australia, British journal of politics and international relations, Vol. 9 (3) pp 327-345 Edwiyna, H 2008, Colonialism and Long-Run Growth in Australia: An Examination of Institutional Change in Victoria’s Water Sector During the Nineteenth Century,   Blackwell publishing ltd Vol. 48 (3) pp 266-279 Goldring, J 2003, The Australian court system and its oral tradition, Retrieved April 25, 2009 from http://209.85.229.132/search?q=cache:inbECLUBLQ4J:web.bham.ac.uk/forensic/IAFL03/goldring.doc+How+far+were+Australia%E2%80%99s+legal,+political+